On the rails of Digital Dentistry, modern technologies and the latest generation of restorative materials open now new horizons in the field of Prosthodontics. The implementation in the daily practice of the most advanced technologies, such as CAD-CAM, laser-sintering/melting and 3D-printing, has got a synergic impulse from the enhanced mechanical and manufacturing properties of the new generation of dental materials. Many of these offer undeniable advantages as high aesthetic potential, astounding optical characteristics, reliable mechanical properties, excellent consistency in terms of precision and accuracy due to the manufacturing technologies, and more convenient production timing. These improvements have dramatically widened the restorative choices in tooth- and implant-supported prosthodontics.